SVENSK STANDARD SS-EN ISO 10993-4:2009 - SIS
p38 MAPK regulates ischemia-reperfusion-induced
This tight link is partly attributable to P-selectin, which is functional not only when expressed on the surface of activated platelets and endothelial cells, but also when shed, generating its soluble form, termed sP-selectin. P-Selectin P-selektin Engelsk definition. Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells. 2011-08-17 · P-selectin expression is involved in the pathophysiology of biologically active arterial thrombus and endothelial activation after a transient ischemic event. Fucoidan is a polysaccharidic ligand of P-selectin, with a nanomolar affinity. In the present study, we propose a new approach of P-selectin molecular imaging based on radiolabeled fucoidan.
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A set of P-selectin was purchased from Randox Laboratories Limited (UK). The Potential of the Quick Detection of Selectins Using Raman Spectroscopy to Discriminate Lung Cancer Patients from Healthy Subjects 2017-11-06 · P-selectin is one of the first cell surface molecules to be expressed on the endothelial cell in response to inflammatory stimuli, and triggers initial neutrophil rolling along the microvascular endothelium (1,10,23,25,31,38,46). Its expression on the endothelial cell lumenal P-Selectin (also called GMP-140) expressed on activated platelets and endothelial cells. Selectins interact with specific carbohydrates expressed by activated endothelial cells, monocytes, and neutrophils. In this video we discuss the three different types of selectins and their involvement in the immune system. 2007-07-15 · Ma, Y-Q., Plow, E.F. & Geng, J.-G.
Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells. 2011-08-17 · P-selectin expression is involved in the pathophysiology of biologically active arterial thrombus and endothelial activation after a transient ischemic event.
Systematic Analysis of In Vitro Cell Rolling Using a Multi-well
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Kinetics of platelet P-selectin mobilization : Concurrent surface
Isotyp, IgG1. ImmunoChemistry, Yes. By enzyme-linked immunosorbent assay, platelet surface expression of P-selectin was measured to estimate the state of activation on adherence. Mg2+ Knowledge concerning the neurobiological importance of platelets in Alzheimers disease (AD) is sparse. P-selectin, which is located together with beta-amyloid P-selectin mediates neutrophil rolling and recruitment in acute pancreatitis. Artikel i interactions in the pancreas remain elusive, but selectins may play a role.
VLA-4 has a crucial role in eosinophil arrest, and arrest is enhanced by exposure to chemoattractants. P‑Selectin/CD62P in Mouse Liver. P-Selectin/CD62P was detected in perfusion fixed frozen sections of mouse liver using Goat Anti-Mouse/Rat P-Selectin/CD62P Antigen Affinity-purified Polyclonal Antibody (Catalog # AF737) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. Definition of p-selectin in the Definitions.net dictionary. Meaning of p-selectin.
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Exogenous administration of thrombin resulted in a marked and rapid, dose-dependent increase in the surface P-selectin expression within 10 min of stimulation (Fig.
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SVENSK STANDARD SS-EN ISO 10993-4:2009 - SIS
Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface. ELISA kits for the study of the target, P-Selectin are available in ready-to-use formats. The protein is also known as selectin P or SELP. It is a 830-residue protein with a membrane localization.
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It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex ) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate The adhesion molecule P-selectin (CD62P) is of interest because of its role in modulating interactions between blood cells and the endothelium, and also because of the possible use of the soluble form as a plasma predictor of adverse cardiovascular events. P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. P-selectin, the largest selectin, is stored in α-granules of platelets and in Weibel–Palade bodies of endothelial cells, and is translocated to the cell surface of activated endothelial cells and platelets. E-selectin is not expressed under baseline conditions, except in skin microvessels, but is rapidly induced by inflammatory cytokines.